Illustration showing the five stages of mitosis. The spindle is a structure made of microtubules, strong fibers that are part of the cell’s skeleton.
#Spindle biology full
The single cell then pinches in the middle to form two separate daughter cells each containing a full set of chromosomes within a nucleus.This line is referred to as the metaphase plate. A membrane forms around each set of chromosomes to create two new nuclei. Spindle fibers align the chromosomes along the middle of the cell nucleus.At each pole of the cell a full set of chromosomes gather together.The sister chromatids are then pulled apart by the mitotic spindle which pulls one chromatid to one pole and the other chromatid to the opposite pole.The mitotic spindle fibres attach to each of the sister chromatids.The spindle grows between the centrosomes as they move apart. Its job is to organize the chromosomes and move them around during mitosis. The centrioles are now at opposite poles of the cell with the mitotic spindle fibres extending from them. The spindle is a structure made of microtubules, strong fibers that are part of the cell’s skeleton.The chromosomes line up neatly end-to-end along the centre (equator) of the cell.The mitotic spindle, consisting of the microtubules and other proteins, extends across the cell between the centrioles as they move to opposite poles of the cell.At the end of prophase the membrane around the nucleus in the cell dissolves away releasing the chromosomes.The chromosomes pair up so that both copies of chromosome 1 are together, both copies of chromosome 2 are together, and so on.Each chromosome is composed of two sister chromatids, containing identical genetic information.The chromosomes condense into X-shaped structures that can be easily seen under a microscope.During interphase, microtubules extend from these centrosomes. From these databases we identified new markers for the different spindle tissues and identified the differentiation stages the spindle capsule cells undergo.Outside of the nucleus are two centrosomes, each containing a pair of centrioles, these structures are critical for the process of cell division.The DNA in the cell is copied in preparation for cell division, this results in two identical full sets of chromosomes.If not corrected in time, mistakes made during mitosis can result in changes in the DNA that can potentially lead to genetic disorders.The major purpose of mitosis is for growth and to replace worn out cells.During mitosis one cell divides once to form two identical cells.
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